The Restylane® Family of Fillers

While those of you reading this page on Dr. Kunkel’s website surely know the name Restylane — the world’s first dermal filler — you probably don’t know the name Galderma. Galderma is a Swiss company that makes Restylane. On this page, we’ll get into a little bit about Galderma, and then into the various Restylane fillers, Dr. Kunkel offers at his Fort Worth practice.

Beautiful face of young woman for Aesthetics facial skincare concept anti-wrinkle forehead botox restylane injection by cosmetic plastic surgeon beautician.

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What is Galderma? What does it do for dermatology and skincare?

Based in Lausanne, Switzerland, Galderma bills itself as the “world’s largest independent global dermatology company.” Galderma says its corporate goal is to “enhance the quality of life by delivering science-based solutions for skin health over the course of people’s lives.”

Toward that aim, Galderma produces various skincare products, everything from Proactive (and various other products you haven’t heard of) for acne treatment to the popular skincare lotion Cetaphil to a product to treat rosacea called Mirvaso, among others.

Of course, Galderma is more known for its aesthetic products: the Restylane® line of dermal fillers, Sculptra® (a long-lasting synthetic filler), and Dysport® (a botulinum toxin product very similar to BOTOX®).

What is Restylane?

Horizontalshot of attractive woman cosmetologist standing and holding up syringe filled with hyaluronic acid, being ready for doing anty aging injection for her client. Aethetic medicine concept.Restylane® was the flagship product, the first dermal filler. It remains very popular around the world. It targets marionette lines, nasolabial folds, and other wrinkles by adding volume beneath the wrinkle or crease and pushing the surface skin upward. Its results last from 6-9 months.

What is Restylane Lyft?

Restylane® Lyft adds volume to the cheeks and corrects smile lines. Lyft also can be used to replace volume loss on the hands (see section below). Results last from one year to 18 months.

What is Restylane Refyne?

Restylane® Refyne was approved by the FDA in December 2016. This addition to the Restylane® line (along with Defyne, see below) is used to correct smile (marionette) lines and nasolabial folds. Refyne is specifically formulated to treat mild to moderate lines and wrinkles. Galderma has cross-linked the gel in Restylane® Refyne and Defyne to help support the patient’s natural expressions — for real-life results that help maintain natural movement when smiling, frowning, or otherwise moving your mouth.

What is Restylane Defyne?

Approved along with Refyne, Restylane® Defyne also specifically targets nasolabial folds and marionette lines. The difference is that Defyne is designed for use on moderate to severe creases and lines. Both Refyne and Defyne provide results that last up to one year.

What are the benefits of Restylane fillers?

Young female with clean fresh skin. A shot of a beautiful woman's face and neck. A medical concept image of how a filler works under the skin.True to their name, Restylane fillers simply “fill” in areas where declining collagen production and thinning skin have allowed creases and lines to form. These occur all around the mouth in the form of smile lines, parentheses lines, marionette lines, and barcode lines. Restylane Lyft returns volume to sunken cheeks. The value for our patients is to instantly look younger as these wrinkles and lines are erased. In the cheeks, fuller cheeks are one of the tenets of a younger-looking face.

All of the Restylane® fillers are approved by the FDA. In fact, the original Restylane® was the first dermal filler approved by the FDA for use in the United States. Today, it remains one of the most popular dermal fillers in the world. To expand the benefits for patients, Galderma has added the additional fillers discussed on this page. They target different areas and provide great results for our patients from Fort Worth and the surrounding areas.

Also, Restylane® fillers are completely noninvasive; they don’t require any recovery, and because they are made from hyaluronic acid patients tolerate them very well.

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Can Restylane be used for hand rejuvenation?

In May 2018, Restylane® Lyft received FDA approval for use on the hands. It was approved to treat age-related volume loss on the back of the hands.

The hands are often overlooked as a marker of aging, but fat volume loss, declining collagen production, thinning skin, and overall sun damage can make your tendons, veins, and the metacarpal bones stick out. This can make your hands look older than anywhere else on your body, leaving them skeletal and bony.

Dermal fillers have been used “off label” on the hands for years, but the FDA approval of Lyft for the hands is a big step forward. Dr. Kunkel injects Lyft underneath the skin, but above the connective tissue that covers the tendons, bones, vessels, and nerves. Patients notice instant volume improvement in their hands, and these improvements last for about six months.

What are the side effects with Restylane fillers?

Because Restylane® is made primarily with hyaluronic acid (which occurs naturally in the human body), allergic reactions are almost unheard of. The common side effects with all dermal fillers are swelling, redness, pain, bruising, tenderness, and itching at the injection sites after your session. Some patients have been known to develop headaches for the first day or two, but this is rare. These side effects are typically mild but may last for up to a week when treating smile and marionette lines.

Occasionally, lumps will form at the injection sites. This is rare, but if this happens, they can be quickly resolved by an injection of hyaluronidase. This is an enzyme that instantly degrades the hyaluronic acid, eliminating the lump.

What’s most important with the use of dermal fillers is the experience of the injector. A board-certified plastic surgeon, Dr. Kunkel has extensive training and experience with the entire Restylane® line, so you can be sure you’ll get the results you’re seeking.

There isn’t any downtime with any Restylane® filler.

Is it painful to have Restylane filler injections?

Cosmetologist performs Restylane injections for anti wrinkle and aging skin on the chin and on the face of a beautiful woman in a beauty salon. Cosmetology concept.Restylane fillers are not injected into great depth, and they are injected with a very fine needle. Still, to ensure patient comfort we apply topical numbing anesthetic prior to every filler session.

Are Restylane fillers safe?

As mentioned above, the various Restylane fillers have all been approved by the FDA, along with other health organizations around the world. Because they are made from hyaluronic acid, a naturally occurring substance in the human body responsible for hydrating, plumping, and firming the skin, reactions to any of these fillers are almost non-existent. These are safe, effective treatments that have been performed millions of times around the globe.

How should I care for my skin after a dermal filler injection?

There isn’t any special care necessary following your injection session at Dr. Kunkel’s. You should refrain from rubbing the injection sites for a day or so to let the filler settle into place. That’s about it.


Schedule a Consultation Today!

If you’re interested in learning more about Restylane fillers please contact us for a consultation at (817) 335-5200 or fill out our contact us form. We will discuss your needs and concerns, and determine your best course of action.



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